Industry News: Everything You Need To Know About Enobosarm

Drugs are not only of serious concern for the common public; in fact, it is no longer new to us if we hear athletes involved in drug abuse.

Over the past few decades, the community of athletes has pushed for stricter policies and regulations for fair and just competitions that entail prohibition of drugs potential for the abuse of athletes to boost their stamina, endurance, and performance. While this is the case, there are still reports that show how alarming drug abuse among athletes is, and this deserves attention from concerned organizations and governments around the globe.

Drug abuse cases come in many forms. Some say that they use drugs for the treatment of physical pain for doing strenuous activities, while others claim that drugs are helpful for them to self-treat mental illnesses arising from a large number of stressors that come with their chosen career. Whatever the circumstances are, there is a global call for the prohibition of drug abuse and regulation of drug usage among athletes across nations.

One of the most popular drugs with a high potential abuse in athletes and sports enthusiasts is ostarine, also known as enobosarm. Based on reports, the said drug has gained popularity for its anabolic effects on the muscles. According to the reviews of users, the drug has very similar results to steroids and prohormones.

Established in the year 1999, the World Anti-Doping Agency (WADA) envisions a clean, drug-free sports all over the world. It is one of the primary organizations that monitors and resolves issues on drug abuse that athletes are involved to. In 2008, WADA has emphasized the potential abuse of selective androgen receptor modulator (SARM), where enobosarm and andarine belong to.


Related Reading: Everything You Need to Know About WADA


What is Enobosarm?

Enobosarm – with the full chemical name (2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-propanamide – is a selective androgen receptor modulator developed by GTX Inc., a pharmaceutical company based in Memphis, Tennessee. It is also commonly known as S22, SARM S-22, and MK-2866, and was produced primarily to prevent or treat muscle wasting. Currently, GTX Inc. considers the drug as investigational and experimental for the treatment of breast cancer.

enobosarm ostarine chemical structure

It basically targets and acts on androgen receptors, instead of converting to estrogen after entering the body. The androgen receptors, then, produce growth factors that boost protein synthesis in the body that would then result to increased lean muscle. Similar to anabolic steroids, the drug also increases nitrogen retention.

As it has significant effects on both muscle and bone tissues, it can be potentially used as medical treatment for atrophy, sarcopenia and cachexia, as well as for hormone replacement therapy, specifically testosterone.

Ostarine or enobosarm belongs to SARM, a chemical class that create anabolic activity with androgen receptors, and have been developed since the early 2000. Compared to  other anabolic steroids, SARMs do not have androgenic activity in non-skeletal muscle tissues. Having said this, SARMs are promising in terms of the ability to increase one’s lean body mass. Because of this, enobosarm has been one of the drugs which captured the attention and interest of the bodybuilding and weightlifting communities.

Currently, the drug is being marketed as a dietary and nutritional supplement. As such, it has become so controversial because of debates and investigations whether or not it should be put under the jurisdiction of the Food and Drug Administration (FDA).

Popular supplements that carry enobosarm include MK-2866 by SARMS1, OSTAR1NE MK-2866 by Olympus Labs, and Ostarine by Thanos Labs, among others.

Why is it being abused?

As aforementioned, enobosarm has the ability to boost one’s performance in various sports. Some people whose goal is to quickly attain a certain body mass will rely on drugs that would promise such result. Also, given that the drug is a non-steroidal androgen receptor, it claims that users will experience reduced side effects compared to traditional steroids.


See Also: What are Anabolic Steroids?


Some individuals and companies are also giving easy access to the drug, and transactions are made much easier when done online. This ease in purchase increases the curiosity of people who would want to try the drug. Sellers would only tell you about the effects which people might think are positive, but the facts that get filtered out in the process are the ones that bring the worst effects to the users.

The drug has also gained the interest of the public because it is purported to be the best substitute for anabolic steroids, but with fewer side effects. For people who engage in more challenging physical activities, enobosarm can also be an abusive drug because it said to have an ability to repair joints that have been damaged, improve the density of bones, and provide body protection from injuries.

Effects of Using Enobosarm

Enobosarm has significant effects on the human body. As it is commonly used as a booster for body-building, it is known to decrease body fat and increase one’s lean muscle. Regular intake may result to considerable muscle strength and performance, better endurance to lift heavy materials, and extended physical activities. It also improves the mobility of joints, tendons, and ligaments, and also increases the strength and density of bones.

The process of recomping is said to be where enobosarm is truly reliable. What the drug does is to take away calories from fat stores, and redirects them to the muscle tissue. In addition, the drug also stimulate testosterone levels in the brain, bones, and muscles.

While there are considered positive effects of the drug, it has also a number of negative effects to the human body. Long-term users have reported that enobosarm affects the male reproductive system such as a decrease in sperm count and flow, shrinking of the testicles, erectile dysfunction, decline in testosterone production, infertility, and increased possibility of prostate cancer.

The abuse of the drug is also said to manifest on the skin through increased oiliness of skin, scalp and hair, breakouts on the back, occurrence of cysts, and even jaundice (yellowing of the skin). The use of the drug may also increase one’s risk to be infected by blood-borne infections such as HIV/AIDS and hepatitis.

Health effects on men and women also include increased fluid retention, liver disease and damage, blood clots, cardiovascular diseases such as alterations in heart structure, decrease in good cholesterol and increase in the body’s bad cholesterol. Psychological effects include depression, lack of concentration, anorexia, insomnia, anxiety leading to suicidal tendencies.

Legality of Enobosarm Use

In the United Kingdom and United States, enobosarm and most known SARMs can be legally purchased in the market. It can be used as part of a training regime, to specifically increase lean muscle mass gain in the bulking phase of the training program. For others, it is a reliable drug that boosts one’s capacity to maintain body structure and stamina over a short recovery period.

Enobosarm and other types of SARMs are prohibited among athletes, and have been listed under the WADA Prohibited List since 2008. The said list includes prohormones and steroids. For the general public, however, the drug is not illegal; only professional athletes are restricted to its use.

While all drugs classified as SARMs have been prohibited by the World Anti-Doping Agency because of their ability to artificially enhance one’s performance, the drug is not within the scope of the Designer Anabolic Steroid Control Act of 2014 (DASCA). Still, the Athlete Guide to the 2016 Prohibited List enumerates the substances they restrict, and enobosarm falls under the category S1 or those classified as anabolic agents.

Conclusion

People who are into sports should always remind themselves that there is no easy way to attain the goal of being good at their chosen craft. The point of doing sports, to begin with, is to challenge oneself to perform physical activities that would help become the best in the craft. There is a natural and fair way of being good at something; in sports, that is almost the case.

Athletes should always put in mind that using boosters or cheat pills is a sign of cheating — on themselves, on the sports they claim to love, and on the whole sporting community. Based on the number of reports related to abuse of certain drugs to enhance their performance, athletes are challenged with a stronger temptation to take the easy way to do things. In the real world, especially in sports, the easy way is most likely not the way that is worth the risk.

People who rely on drugs run the risk of getting caught and being disqualified from competitions — for the rest of their lives. While it gets tempting for people to try new things, one’s health should never be compromised. If common people should be reminded of the products they take in, athletes should be more cautious of what they choose to use as part of their training routines.
Athletes may have the best equipment, the best suits, the best training programs, but without a healthy body that is free from drugs that might have negative effects in the long run, they constantly put themselves in the greater possibility of losing.

Related Reading:

Everything You Need to Know About Blood Doping

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