Tricyclic Antidepressants

Tricyclic Antidepressants- Drug Facts:

Tricyclic Antidepressants and tetracyclic antidepressants are heterocyclic chemical components used predominately as antidepressants.  The drug was introduced to the public in 1950.  Chemical changes occur in the brain when a person is depressed.  Tricyclic Antidepressants are used to stabilize mood.

Description & Overview:
Central Nervous System Depressant

Other Names – Brands:
Amitriptyline
– Amoxapine
– Desipramine (Norpramin)
– Doxepin
– Imipramine (Tofranil, Tofranil-PM)
– Maprotiline
– Nortriptyline (Pamelor)
– Protriptyline (Vivactil)
– Trimipramine (Surmontil)

Used Illegally:
Downers
– After Taking Other Illegal Drugs to Obtain “High”
– Used in Combination With Other Drugs: Alcohol, Marijuana

Medically Used to Treat:
Parkinson’s Disease
– Off-Label for Sleep
– Unapproved Uses of Approved Drugs

Street Names for Tricyclic – Antidepressants:
– Blue Angels
– Blue Birds
– Vivactil
– Anafranil
– Janimine
– Tofranil
– TCA

How Tricyclic – Antidepressants Affects the Brain:
Affect Chemical Messengers in the Brain
– Neurotransmitters
– Used to Communicate Between Brain Cells
– Change the Level of One or More Neurotransmitters
– Block the Absorption
– Block Reuptake of Neurotransmitters Serotonin
– Block Reuptake of Norepinephrine

Results:
- Make These Chemicals More Available in the Brain
– Helps Brain Cells Send Messages
– Helps Brain Cells Receive Messages
– Effects Mood

Short-Term Effects of Using Tricyclic – Antidepressants:
Drowsiness
– Dry Mouth
– Blurred Vision
– Constipation
– Dizziness

Long-Term Effects of Using Tricyclic – Antidepressants:
Addiction
– Delayed Orgasm
– Low Sex Drive
– Urinary Retention
– Increased Heart Rate
– Disorientation
– Confusion
– Low Blood Pressure
– Light Headed
– Fatique
– Nausea
– Increased Appetite
– Weight Gain
– Headache
– Sensitivity to Sunlight
– Seizures